![]() Andexxa is the only antidote to date that can reverse these effects. While effective in reducing the risk of stroke or systemic embolism, both can lead to life-threatening and uncontrolled bleeding. Rivaroxaban (sold under the brand name Xarelto) and apixaban (sold under the brand name Eliquis) are anticoagulants often prescribed to patients for preventing blood clots. ![]() The sole purpose of Andexxa is to reverse the Factor Xa inhibitors, apixaban (Eliquis) and rivaroxaban (Xarelto). While its potential is great, Andexxa is not recommended for treating all conditions related to uncontrolled bleeding. Acting as a biological agent, Andexxa has successfully been documented to reverse blood loss and acts as a reversal of Factor Xa inhibitors, which are classes of anticoagulant drugs. Orphan Drug and FDA Breakthrough Therapy designations and was also approved under the FDA’s Accelerated Approval Pathway. Abington Memorial Hospital (Abington-Jefferson Health) is proud to announce that we will be one of the first forty hospitals in the United States to receive the first limited supply! Now equipped with Andexxa, we will be able to assist and treat our patients in more ways than ever before.Īndexxa (also known as Andexanet alfa) has been developed to combat diseases that lead to uncontrollable bleeding and was developed by Portola Pharmaceuticals. On May 3, 2018, the Food and Drug Administration (FDA) approved the use of Andexxa, the first available antidote for patient’s taking the blood thinners Xarelto or Eliquis and who experience serious bleeding. Abington Memorial Hospital (Abington-Jefferson Health) Selected for Early Supply Program of Andexxa (reversal agent for the blood thinners Xarelto & Eliquis)
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